NORCURON®
Composition
Each 1 ml of Norcuron® contains 2 mg of vecuronium bromide.
General Description:
Norcuron® (vecuronium bromide) is a non-depolarising neuromuscular blocking agent, chemically designated as the aminosteroid. Norcuron blocks the transmission process between the motor nerve-ending and striated muscle by binding competitively with acetylcholine to the nicotinic receptors located in the motor end-plate region of striated muscle. Unlike depolarising neuromuscular blocking agents, such as succinylcholine, Norcuron does not cause muscle fasciculation. Within 90 to 120 seconds following intravenous administration of a dose of 0.08 to 0.10 mg vecuronium bromide per kg body weight (approximately 2xED90 under neurolept anaesthesia), good to excellent conditions for endotracheal intubation occur and within 3 to 4 minutes following administration of these dosages, general muscle paralysis adequate for any type of surgery is established.
Indications
Norcuron® is indicated as an adjunct to general anesthesia to facilitate endotracheal intubation and to provice skeletal muscle relaxation during surgery.
Contraindications
Former anaphylactic reaction to vecuronium or the bromide ion
Detail prescribing information:
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