Each 1 ml of Norcuron® contains 2 mg of vecuronium bromide.
Norcuron® (vecuronium bromide) is a non-depolarising neuromuscular blocking agent, chemically designated as the aminosteroid. Norcuron blocks the transmission process between the motor nerve-ending and striated muscle by binding competitively with acetylcholine to the nicotinic receptors located in the motor end-plate region of striated muscle. Unlike depolarising neuromuscular blocking agents, such as succinylcholine, Norcuron does not cause muscle fasciculation. Within 90 to 120 seconds following intravenous administration of a dose of 0.08 to 0.10 mg vecuronium bromide per kg body weight (approximately 2xED90 under neurolept anaesthesia), good to excellent conditions for endotracheal intubation occur and within 3 to 4 minutes following administration of these dosages, general muscle paralysis adequate for any type of surgery is established.
Norcuron® is indicated as an adjunct to general anesthesia to facilitate endotracheal intubation and to provice skeletal muscle relaxation during surgery.
Former anaphylactic reaction to vecuronium or the bromide ion
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