ZOLETA™ is a potent and highly specific nonsteroidal aromatase inhibitor. It inhibits the aromatase enzyme by competitively binding to the haem of the cytochrome P450 subunit of the enzyme, resulting in a reduction of estrogen biosynthesis in all tissues. Letrozole exerts its antitumor effect by depriving estrogen dependent breast cancer cells of their growth stimulus. In postmenopausal women, estrogens are derived mainly from the action of the aromatase enzyme, which converts adrenal androgens, primarily androstenedione and testosterone to oestrone (El) and oestradiol (E2).
Letrozole (Zoleta) lowers estrogen levels in postmenopausal women, which may slow the growth of certain types of breast tumors that need estrogen to grow in the body.
you are allergic to any ingredient of letrozole.
If anyone have
if you also take tamoxifen.
Breast cancer : 1 tab / day for 6 months
Ovulation induction : 2.5 mg/ day 3 tablets on day 3’rd to 7’th day of menstruation (5 days)
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
It is recommended to withdraw this drug after physician consultation.
Common side effects may include:
Store at room temperature (between 15-30° C)
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