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LeneaTM stabilizes the hypothalamic-pituitary system after failure of the ovarian function in the clymactric. This central effect results from a favorable   combination of hormonal properties, e.g. estrogenic, progestational and weak  androgenic activities, which are demonstrated by the following effects: LeneaTM in a daily oral dose of 2.5 mg, suppresses the gonadotrophin levels in  postmenopausal women and inhibits ovulation in fertile women. In this same dosage, LeneaTM does not stimulate the endometrium in postmenopausal women. Only a very few patients showed slight proliferation; the degree of proliferation did not increase with the duration of treatment. A stimulatory effect on vaginal mucosa was also seen. The same dosage of LeneaTM was shown to inhibit postmenopausal bone loss; menopausal complaints, specially vesomotor complaints such as hot flushes and sweating, are suppressed; libido and mood are favourably affected. Like other steroidal compounds, Tibolone BP is metabolized in the liver and converted to metabolites which are excreted in urine and faeces. Some of the metabolites may contribute to the biological effects of the drug.


What is Lenea and what is it used for?

  • Treatment of symptoms resulting from the natural or surgical menopause in postmenopausal women.
  • Prevention of osteoporosis in women who have gone through the menopause and are at high risk of fractures, but cannot take other medicines used to prevent osteoporosis.

Before you take Lenea, Do not take this medicine and tell your doctor if

The following medicines may interact with tibolone:







Drugs that thin the blood such as warfarin

Take special care while taking Lenea

Before taking tibolone, tell your doctor if you are allergic to it; or to other hormone replacement therapies (HRT); or if you have any other allergies.

How and when to take Lenea

  • Treatment of symptoms resulting from the natural or surgical menopause: The recommended dose is 2.5 mg once daily.
  • Prevention of post-menopausal bone mineral density loss: The recommended dose is 2.5 mg once daily.

If you forget to take Lenea

Don’t take double dose in one day

If you stop taking Lenea

Need to continue for 6 months

Possible side effects

  • Vaginal infection (including thrush)
  • Increased vaginal secretions
  • Thickening of the lining of the womb or cervix
  • Acne
  • Changes in liver tests (revealed on blood testing)

How to store Lenea

Store at room temperature, Below 25°C or in refrigerator. Do not Freeze. Protect from Sunlight and Moisture.