CardifortTM 5 (Amlodipine) is a Calcium antagonist of the Dihydropyridine group and inhibits the transmembrane influx of Calcium ion into cardiac & smooth muscle. It is used for the treatment of hypertension and angina pectoris CardifortTM 5 is slowly and incompletely absorbed, with 60-80% of an oral dose reaching the systemic circulation. Plasma half life ranges from 30-60 hrs (mean 35.7 hrs). CardifortTM 5 is extensively metabolized in the liver prior to excretion with only about 5% unchanged drug excreted in the urine.
Cardifort contains Amlodipine which is a calcium antagonist of the Dihydropyridine group and inhibits the transmembrane influx of Calcium ion into cardiac & smooth muscle. It is used for Hypertension, Chronic Stable Angina, and Vasospastic Angina.
You should not take Cardifort if you are allergic to it. To make sure amlodipine is safe for you, tell your doctor if you have: liver disease; or a heart valve problem called aortic stenosis.
Although Cardifort is excreted primarily via kidney, mild renal impairment does not appear to have an effect on the plasma concentrations. Severe renal impairment may however require a dosage reduction. Amlodipine is not dialyzable.
Take Cardifort exactly as prescribed by your doctor. You may take amlodipine with or without food. Take the medicine at the same time each day.
Take the missed dose as soon as you remember. If you are more than 12 hours late, skip the missed dose. Do not take extra medicine to make up the missed dose.
Do not stop taking this medicine without talking to your doctor. You should not stop taking Cardifort just because you feel better.
Cardifort is well tolerated. Headache, oedema, fatigue, nausea, flushing, dizziness, gum hyperplasia, erythema multiforme are reported.
Keep medicine out of reach of children. Store in a cool and dry place.
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